{"id":686,"date":"2024-04-12T15:23:38","date_gmt":"2024-04-12T07:23:38","guid":{"rendered":"http:\/\/www.zenith-vn.com\/?p=686"},"modified":"2024-04-22T15:42:03","modified_gmt":"2024-04-22T07:42:03","slug":"paracetamol-acetaminophen-2","status":"publish","type":"post","link":"https:\/\/www.zenith-vn.com\/vi\/paracetamol-acetaminophen-2\/","title":{"rendered":"Paracetamol (Acetaminophen)"},"content":{"rendered":"
Ti\u00eau chu\u1ea9n<\/strong><\/strong><\/td>LiBP2018\/USP42<\/td><\/tr>
V\u1ebb b\u1ec1 ngo\u00e0i<\/strong><\/strong><\/td>B\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng ho\u1eb7c g\u1ea7n nh\u01b0 tr\u1eafng.<\/td><\/tr>
\u0111\u1ed9 h\u00f2a tan<\/strong><\/td>\u00cdt tan trong n\u01b0\u1edbc, d\u1ec5 tan trong r\u01b0\u1ee3u, r\u1ea5t \u00edt tan trong methylene chloride.<\/td><\/tr>
Nh\u1eadn bi\u1ebft<\/strong><\/td>\u0110i\u1ec3m n\u00f3ng ch\u1ea3y: 168-172,0oC
IR:
ph\u00f9 h\u1ee3p v\u1edbi ph\u1ed5 thu \u0111\u01b0\u1ee3c v\u1edbi Paracetamol CRS<\/td><\/tr>
Nh\u1eefng ch\u1ea5t li\u00ean quan<\/strong><\/strong><\/td>T\u1ea1p ch\u1ea5t J (chloroacetanilide \u2264 10ppm)
T\u1ea1p ch\u1ea5t K (4-aminophenol \u2264 50ppm)
T\u1ea1p ch\u1ea5t F (4-nitrophenol \u2264 0,05%)
B\u1ea5t k\u1ef3 t\u1ea1p ch\u1ea5t n\u00e0o kh\u00e1c \u2264 0,05%
T\u1ed5ng t\u1ea1p ch\u1ea5t kh\u00e1c \u2264 0,1%<\/td><\/tr>
T\u1ed5n th\u1ea5t khi s\u1ea5y<\/strong><\/strong><\/td>\u2264 0,5%<\/td><\/tr>
D\u01b0 l\u01b0\u1ee3ng khi \u0111\u00e1nh l\u1eeda<\/strong><\/strong><\/td>\u2264 0,1%<\/td><\/tr>
x\u00e9t nghi\u1ec7m<\/strong><\/strong><\/td>99.0-101.0% (t\u00ednh tr\u00ean c\u01a1 s\u1edf kh\u00f4)<\/td><\/tr>
Gi\u1edbi h\u1ea1n vi sinh v\u1eadt<\/strong><\/strong><\/td>T\u1ed5ng s\u1ed1 vi khu\u1ea9n hi\u1ebfu kh\u00ed kh\u00f4ng qu\u00e1 2000cfu\/g
N\u1ea5m m\u1ed1c v\u00e0 n\u1ea5m men k\u1ebft h\u1ee3p kh\u00f4ng \u0111\u01b0\u1ee3c v\u01b0\u1ee3t qu\u00e1 200cfu\/g
S\u1ef1 v\u1eafng m\u1eb7t c\u1ee7a Escherichia coli<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

C\u1ea5u tr\u00fac ph\u00e2n t\u1eed:<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

C\u00f4ng th\u1ee9c ph\u00e2n t\u1eed:<\/strong>\u00a0\u00a0C8<\/sub>H9<\/sub>KH\u00d4NG2<\/sub><\/p>\n\n\n\n

Tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/strong>:<\/strong>\u00a0\u00a0151.16<\/p>\n\n\n\n

S\u1ef1 mi\u00eau t\u1ea3<\/strong>:<\/strong> B\u1ec1 ngo\u00e0i c\u1ee7a n\u00f3 l\u00e0 tinh th\u1ec3 m\u00e0u tr\u1eafng ho\u1eb7c b\u1ed9t tinh th\u1ec3, nhi\u1ec7t \u0111\u1ed9 n\u00f3ng ch\u1ea3y 168-172oC, kh\u00f4ng m\u00f9i, h\u01a1i \u0111\u1eafng, d\u1ec5 h\u00f2a tan trong n\u01b0\u1edbc n\u00f3ng ho\u1eb7c ethanol, h\u00f2a tan trong axeton, h\u1ea7u nh\u01b0 kh\u00f4ng h\u00f2a tan trong n\u01b0\u1edbc l\u1ea1nh v\u00e0 ete d\u1ea7u m\u1ecf.<\/p>\n\n\n\n

\u1ee8ng d\u1ee5ng<\/strong><\/strong>:<\/strong>N\u00f3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb s\u1ed1t do c\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng ho\u1eb7c c\u00fam v\u00e0 c\u0169ng \u0111\u1ec3 gi\u1ea3m c\u00e1c c\u01a1n \u0111au t\u1eeb nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh nh\u01b0 nh\u1ee9c \u0111\u1ea7u, \u0111au kh\u1edbp, \u0111au n\u1eeda \u0111\u1ea7u, \u0111au r\u0103ng, \u0111au c\u01a1, \u0111au d\u00e2y th\u1ea7n kinh v\u00e0 \u0111au b\u1ee5ng kinh.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u0111\u00f3ng g\u00f3i <\/strong> <\/strong><\/strong><\/strong>: 25kg\/bao ho\u1eb7c theo y\u00eau c\u1ea7u c\u1ee7a kh\u00e1ch h\u00e0ng.<\/p>\n\n\n\n

Kho<\/strong> <\/strong><\/strong><\/strong>: B\u1ea3o qu\u1ea3n trong h\u1ed9p k\u00edn, tr\u00e1nh \u00e1nh s\u00e1ng v\u00e0 b\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng. B\u1ea3o v\u1ec7 kh\u1ecfi \u0111\u1ed9 \u1ea9m v\u00e0 nhi\u1ec7t.<\/p>\n\n\n\n

H\u1ea1n s\u1eed d\u1ee5ng :<\/strong> 48 th\u00e1ng k\u1ec3 t\u1eeb ng\u00e0y s\u1ea3n xu\u1ea5t khi \u0111\u01b0\u1ee3c b\u1ea3o qu\u1ea3n trong \u0111i\u1ec1u ki\u1ec7n t\u1ed1t.<\/p>\n\n\n\n

\u0110\u01a1n h\u00e0ng t\u1ed1i thi\u1ec3u<\/strong><\/strong><\/strong>:<\/strong>\u00a01000kg<\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Standard LiBP2018\/USP42 Appearance White or almost white crystalline powder. Solubility Sparingly soluble in water, freely soluble in alcohol, very slightly soluble in methylene chloride. Identification Melting point: 168-172.0\u2103IR\uff1aconsistent with the spectrum obtained with Paracetamol CRS Related substances Impurity J (chloroacetanilide\u00a0\u2264\u00a010ppm)Impurity K (4-aminophenol \u2264\u00a050ppm)Impurity F (4-nitrophenol \u2264\u00a00.05%)Any other impurity \u2264\u00a00.05%Total of other impurities \u2264\u00a00.1% Loss on […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-686","post","type-post","status-publish","format-standard","hentry","category-pharmaceutical-ingredients"],"_links":{"self":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/comments?post=686"}],"version-history":[{"count":1,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/686\/revisions"}],"predecessor-version":[{"id":689,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/686\/revisions\/689"}],"wp:attachment":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/media?parent=686"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/categories?post=686"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/tags?post=686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}