{"id":651,"date":"2024-04-12T13:27:28","date_gmt":"2024-04-12T05:27:28","guid":{"rendered":"http:\/\/www.zenith-vn.com\/?p=651"},"modified":"2024-04-22T16:27:04","modified_gmt":"2024-04-22T08:27:04","slug":"gabapentin","status":"publish","type":"post","link":"https:\/\/www.zenith-vn.com\/vi\/gabapentin\/","title":{"rendered":"Gabapentin"},"content":{"rendered":"
D\u01b0\u1ee3c \u0111i\u1ec3n<\/strong><\/td>USP42<\/td><\/tr>
S\u1ef1 mi\u00eau t\u1ea3<\/strong><\/td>B\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng ho\u1eb7c tr\u1eafng nh\u1ea1t.<\/td><\/tr>
Nh\u1eadn bi\u1ebft<\/strong>:<\/td><\/td><\/tr>
IR<\/td>Ph\u00f9 h\u1ee3p v\u1edbi RT c\u1ee7a \u0111\u1ec9nh ch\u00ednh trong HPLC v\u1edbi USP Gabapentin WRS<\/td><\/tr>
pH<\/strong><\/td>6.5~8.0<\/td><\/tr>
N\u01b0\u1edbc<\/strong><\/td>.50,5%<\/td><\/tr>
D\u01b0 l\u01b0\u1ee3ng khi \u0111\u00e1nh l\u1eeda<\/strong><\/td> .110,1%<\/td><\/tr>
Kim lo\u1ea1i n\u1eb7ng<\/strong><\/td>.50%<\/td><\/tr>
Dung m\u00f4i d\u01b0 (Ethanol)<\/strong><\/td>97.00~103.00%<\/td><\/tr>
H\u1ee3p ch\u1ea5t li\u00ean quan:<\/strong><\/td><\/td><\/tr>
T\u1ea1p ch\u1ea5t r\u1eeda gi\u1ea3i s\u1edbm:<\/strong><\/td><\/td><\/tr>
Th\u00e0nh ph\u1ea7n li\u00ean quan \u0111\u1ebfn Gabapentin A<\/td>.110,1%<\/td><\/tr>
Th\u00e0nh ph\u1ea7n li\u00ean quan \u0111\u1ebfn Gabapentin B<\/td>.06%<\/td><\/tr>
Th\u00e0nh ph\u1ea7n li\u00ean quan \u0111\u1ebfn Gabapentin E<\/td>.10%<\/td><\/tr>
T\u1ea1p ch\u1ea5t ri\u00eang l\u1ebb ch\u01b0a bi\u1ebft<\/td>.10%<\/td><\/tr>
T\u1ea1p ch\u1ea5t r\u1eeda gi\u1ea3i mu\u1ed9n:<\/strong><\/td><\/td><\/tr>
B\u1ea5t k\u1ef3 t\u1ea1p ch\u1ea5t ri\u00eang l\u1ebb<\/td>.10%<\/td><\/tr>
T\u1ed5ng t\u1ea1p ch\u1ea5t<\/td>.50,5%<\/td><\/tr>
x\u00e9t nghi\u1ec7m<\/strong><\/td>98.0%~ 102.0%<\/td><\/tr>
Gi\u1edbi h\u1ea1n clorua<\/strong><\/td>.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

C\u1ea5u tr\u00fac ph\u00e2n t\u1eed:<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

C\u00f4ng th\u1ee9c ph\u00e2n t\u1eed:<\/strong>\u00a0C9<\/sub>H17<\/sub>KH\u00d4NG2<\/sub><\/p>\n\n\n\n

Tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/strong>:<\/strong>\u00a0171.237<\/p>\n\n\n\n

S\u1ef1 mi\u00eau t\u1ea3<\/strong>:<\/strong> Gabapentin l\u00e0 b\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng ho\u1eb7c tr\u1eafng nh\u1ea1t c\u00f3 t\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc \u1ed5n \u0111\u1ecbnh \u1edf nhi\u1ec7t \u0111\u1ed9 v\u00e0 \u00e1p su\u1ea5t ph\u00f2ng.<\/p>\n\n\n\n

\u1ee8ng d\u1ee5ng<\/strong><\/strong>:<\/strong>\u00a0<\/p>\n\n\n\n

Gabapentin l\u00e0 m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 GABA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u1ed9ng kinh v\u00e0 \u0111au d\u00e2y th\u1ea7n kinh. Gabapentin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n \u0111\u1ed9ng kinh c\u00f3 c\u01a1n \u0111\u1ed9ng kinh c\u1ee5c b\u1ed9 kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t ho\u1eb7c dung n\u1ea1p th\u1ecfa \u0111\u00e1ng b\u1eb1ng thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh th\u00f4ng th\u01b0\u1eddng, c\u0169ng nh\u01b0 \u0111i\u1ec1u tr\u1ecb b\u1ed5 sung cho b\u1ec7nh nh\u00e2n b\u1ecb \u0111\u1ed9ng kinh c\u1ee5c b\u1ed9 v\u00e0 sau \u0111\u00f3 l\u00e0 \u0111\u1ed9ng kinh to\u00e0n th\u1ec3.<\/p>\n\n\n\n

Gabapentin l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh m\u1edbi. T\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd c\u1ee7a n\u00f3 kh\u00e1c v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh hi\u1ec7n c\u00f3. Gabapentin \u0111\u00e3 cho th\u1ea5y t\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba b\u1ec7nh \u0111\u1ed9ng kinh \u1edf nhi\u1ec1u m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt kh\u00e1c nhau. Ngo\u00e0i ra, n\u00f3 c\u00f2n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt v\u1ec1 co gi\u1eadt, gi\u1ea3m \u0111au v\u00e0 x\u01a1 c\u1ee9ng teo c\u01a1 m\u1ed9t b\u00ean. N\u00f3 c\u0169ng cho th\u1ea5y m\u1ed9t vai tr\u00f2 trong \u0111\u00f3. So v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng co gi\u1eadt kh\u00e1c, gabapentin c\u00f3 \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 v\u1ec1 h\u00e0nh vi v\u00e0 tim m\u1ea1ch h\u01a1n.<\/p>\n\n\n\n

\u0111\u00f3ng g\u00f3i <\/strong><\/strong><\/strong>: Bao 10kg, 15kg, 25kg\/th\u00f9ng<\/p>\n\n\n\n

Kho<\/strong><\/strong>:<\/strong>B\u1ea3o qu\u1ea3n k\u00edn, kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t.<\/p>\n\n\n\n

H\u1ea1n s\u1eed d\u1ee5ng :<\/strong><\/strong><\/strong><\/strong>36 th\u00e1ng k\u1ec3 t\u1eeb ng\u00e0y s\u1ea3n xu\u1ea5t khi \u0111\u01b0\u1ee3c b\u1ea3o qu\u1ea3n trong \u0111i\u1ec1u ki\u1ec7n t\u1ed1t.<\/p>\n\n\n\n

\u0110\u01a1n h\u00e0ng t\u1ed1i thi\u1ec3u<\/strong><\/strong><\/strong>:<\/strong> M\u1ed9t g\u00f3i<\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Pharmacopoeia USP42 Description White or off-white crystalline powder. Identification: IR Conform with the RT of the major peak in HPLC with USP Gabapentin WRS pH 6.5~8.0 Water \u22640.5% Residue on ignition  \u22640.1% Heavy metals \u22640.50% Residual solvents (Ethanol) 97.00~103.00% Related compounds: Early eluting impurities: Gabapentin related components A \u22640.1% Gabapentin related components B \u22640.06% Gabapentin […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-651","post","type-post","status-publish","format-standard","hentry","category-pharmaceutical-ingredients"],"_links":{"self":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/comments?post=651"}],"version-history":[{"count":1,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/651\/revisions"}],"predecessor-version":[{"id":653,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/651\/revisions\/653"}],"wp:attachment":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/media?parent=651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/categories?post=651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/tags?post=651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}