{"id":343,"date":"2023-05-30T17:41:17","date_gmt":"2023-05-30T09:41:17","guid":{"rendered":"http:\/\/www.zenith-vn.com\/?p=343"},"modified":"2024-04-12T11:21:36","modified_gmt":"2024-04-12T03:21:36","slug":"paracetamol-acetaminophen","status":"publish","type":"post","link":"https:\/\/www.zenith-vn.com\/vi\/paracetamol-acetaminophen\/","title":{"rendered":"Paracetamol (Acetaminophen)"},"content":{"rendered":"
ti\u00eau chu\u1ea9n<\/td>BP2018\/USP42<\/td><\/tr>
V\u1ebb b\u1ec1 ngo\u00e0i<\/td>B\u1ed9t tinh th\u1ec3 m\u00e0u tr\u1eafng ho\u1eb7c g\u1ea7n nh\u01b0 tr\u1eafng.<\/td><\/tr>
\u0111\u1ed9 h\u00f2a tan<\/td>\u00cdt tan trong n\u01b0\u1edbc, d\u1ec5 tan trong r\u01b0\u1ee3u, r\u1ea5t \u00edt tan trong methylene chloride.<\/td><\/tr>
Nh\u1eadn bi\u1ebft<\/td>\u0110i\u1ec3m n\u00f3ng ch\u1ea3y: 168-172,0oC IR: Ph\u00f9 h\u1ee3p v\u1edbi ph\u1ed5 thu \u0111\u01b0\u1ee3c v\u1edbi Paracetamol CRS<\/td><\/tr>
Nh\u1eefng ch\u1ea5t li\u00ean quan<\/td>T\u1ea1p ch\u1ea5t J (chloroacetanilide \u2264 10ppm)T\u1ea1p ch\u1ea5t K (4-aminophenol \u2264 50ppm)T\u1ea1p ch\u1ea5t F (4-nitrophenol \u2264 0,05%)B\u1ea5t k\u1ef3 t\u1ea1p ch\u1ea5t n\u00e0o kh\u00e1c \u2264 0,05%T\u1ed5ng c\u00e1c t\u1ea1p ch\u1ea5t kh\u00e1c \u2264 0,1%<\/td><\/tr>
T\u1ed5n th\u1ea5t khi s\u1ea5y<\/td>\u2264 0,5%<\/td><\/tr>
D\u01b0 l\u01b0\u1ee3ng khi \u0111\u00e1nh l\u1eeda<\/td>\u2264 0,1%<\/td><\/tr>
x\u00e9t nghi\u1ec7m<\/td>99.0-101.0% (t\u00ednh tr\u00ean c\u01a1 s\u1edf kh\u00f4)<\/td><\/tr>
Gi\u1edbi h\u1ea1n vi sinh v\u1eadt<\/td>T\u1ed5ng s\u1ed1 vi khu\u1ea9n hi\u1ebfu kh\u00ed kh\u00f4ng qu\u00e1 2000cfu\/g N\u1ea5m m\u1ed1c v\u00e0 n\u1ea5m men k\u1ebft h\u1ee3p kh\u00f4ng \u0111\u01b0\u1ee3c v\u01b0\u1ee3t qu\u00e1 200cfu\/g Kh\u00f4ng c\u00f3 Escherichia coli<\/td><\/tr>
C\u00f4ng th\u1ee9c ph\u00e2n t\u1eed<\/td>C8H9NO2<\/td><\/tr>
Tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/td>151.16<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

C\u1ea4U TR\u00daC PH\u00c2N T\u1eec:<\/p>\n\n\n

\n
\"\"<\/figure><\/div>\n\n\n

\u1ee8ng d\u1ee5ng<\/p>\n\n\n\n

1. X\u1eed l\u00fd n\u01b0\u1edbc th\u1ea3i Dextrose c\u00f4ng nghi\u1ec7p.<\/p>\n\n\n\n

2.Dextrose \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ch\u1ee7 y\u1ebfu l\u00e0m ch\u1ea5t dinh d\u01b0\u1ee1ng \u0111\u1ec3 ti\u00eam (ti\u00eam glucose);<\/p>\n\n\n\n

3.Dextrose trong c\u00f4ng nghi\u1ec7p th\u1ef1c ph\u1ea9m: \u0111\u01b0\u1ee3c \u1ee9ng d\u1ee5ng r\u1ed9ng r\u00e3i trong ng\u00e0nh m\u00eda \u0111\u01b0\u1eddng hi\u1ec7n nay.<\/p>\n\n\n\n

Dextrose l\u00e0 d\u01b0\u1ee1ng ch\u1ea5t kh\u00f4ng th\u1ec3 thi\u1ebfu cho qu\u00e1 tr\u00ecnh trao \u0111\u1ed5i ch\u1ea5t trong c\u01a1 th\u1ec3.<\/p>\n\n\n\n

4. Ng\u00e0nh c\u00f4ng nghi\u1ec7p d\u01b0\u1ee3c ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng tr\u1ef1c ti\u1ebfp trong ng\u00e0nh c\u00f4ng nghi\u1ec7p in v\u00e0 nhu\u1ed9m nh\u01b0 m\u1ed9t ch\u1ea5t kh\u1eed, trong ng\u00e0nh c\u00f4ng nghi\u1ec7p g\u01b0\u01a1ng v\u00e0 quy tr\u00ecnh m\u1ea1 b\u1ea1c m\u1eadt chai n\u01b0\u1edbc n\u00f3ng th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m ch\u1ea5t kh\u1eed.<\/p>","protected":false},"excerpt":{"rendered":"

Tandard BP2018\/USP42 Appearance White or almost white crystalline powder. Solubility Sparingly soluble in water, freely soluble in alcohol, very slightly soluble in methylene chloride. Identification Melting point: 168-172.0\u2103 IR\uff1aConsistent with the spectrum obtained with Paracetamol CRS Related substances Impurity J (chloroacetanilide \u2264 10ppm)Impurity K (4-aminophenol \u2264 50ppm)Impurity F (4-nitrophenol \u2264 0.05%)Any other impurity \u2264 0.05%Total of other impurities \u2264 0.1% Loss […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-343","post","type-post","status-publish","format-standard","hentry","category-pharmaceutical-ingredients"],"_links":{"self":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/comments?post=343"}],"version-history":[{"count":2,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/343\/revisions"}],"predecessor-version":[{"id":396,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/343\/revisions\/396"}],"wp:attachment":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/media?parent=343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/categories?post=343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/tags?post=343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}