Theo c\u00e1c b\u1ea3n tin t\u1eeb London, Anh, c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m GlaxoSmithKline (GSK) th\u00f4ng b\u00e1o r\u1eb1ng C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) \u0111\u00e3 ph\u00ea duy\u1ec7t \u0111\u01a1n xin c\u1ea5p ph\u00e9p thu\u1ed1c m\u1edbi b\u1ed5 sung cho lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh \u0111\u01b0\u1eddng u\u1ed1ng m\u1edbi d\u1ea1ng vi\u00ean n\u00e9n Gepotidacin 750mg (t\u00ean th\u01b0\u01a1ng hi\u1ec7u: \u201cBlujepa\u201d). Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u01b0\u1eddng u\u1ed1ng n\u00e0y \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh l\u1eadu ni\u1ec7u \u0111\u1ea1o v\u00e0 sinh d\u1ee5c kh\u00f4ng bi\u1ebfn ch\u1ee9ng do vi khu\u1ea9n Neisseria gonorrhoeae nh\u1ea1y c\u1ea3m g\u00e2y ra \u1edf b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean v\u00e0 c\u00e2n n\u1eb7ng \u00edt nh\u1ea5t 45 kg, trong tr\u01b0\u1eddng h\u1ee3p c\u00e1c l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb b\u1ecb h\u1ea1n ch\u1ebf ho\u1eb7c kh\u00f4ng c\u00f3.<\/p>\n\n\n\n
Theo c\u00e1c b\u1ea3n tin t\u1eeb London, Anh, c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m GlaxoSmithKline (GSK) th\u00f4ng b\u00e1o r\u1eb1ng C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) \u0111\u00e3 ph\u00ea duy\u1ec7t \u0111\u01a1n xin c\u1ea5p ph\u00e9p thu\u1ed1c m\u1edbi b\u1ed5 sung cho lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh \u0111\u01b0\u1eddng u\u1ed1ng m\u1edbi d\u1ea1ng vi\u00ean n\u00e9n Gepotidacin 750mg (t\u00ean th\u01b0\u01a1ng hi\u1ec7u: \u201cBlujepa\u201d). Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u01b0\u1eddng u\u1ed1ng n\u00e0y \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh l\u1eadu ni\u1ec7u \u0111\u1ea1o v\u00e0 sinh d\u1ee5c kh\u00f4ng bi\u1ebfn ch\u1ee9ng do vi khu\u1ea9n Neisseria gonorrhoeae nh\u1ea1y c\u1ea3m g\u00e2y ra \u1edf b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean v\u00e0 c\u00e2n n\u1eb7ng \u00edt nh\u1ea5t 45 kg, trong tr\u01b0\u1eddng h\u1ee3p c\u00e1c l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb b\u1ecb h\u1ea1n ch\u1ebf ho\u1eb7c kh\u00f4ng c\u00f3.<\/p>\n\n\n\n
C\u00e1c nh\u00e0 khoa h\u1ecdc c\u1ee7a GSK \u0111\u00e3 ph\u00e1t hi\u1ec7n ra r\u1eb1ng Gepotidacin l\u00e0 m\u1ed9t lo\u1ea1i kh\u00e1ng sinh di\u1ec7t khu\u1ea9n thu\u1ed9c nh\u00f3m triaza-naphthyridine m\u1edbi, \u1ee9c ch\u1ebf s\u1ef1 sao ch\u00e9p DNA c\u1ee7a vi khu\u1ea9n th\u00f4ng qua m\u1ed9t v\u1ecb tr\u00ed li\u00ean k\u1ebft \u0111\u1ed9c \u0111\u00e1o, v\u1edbi c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng m\u1edbi l\u1ea1. \u0110\u1ed1i v\u1edbi h\u1ea7u h\u1ebft c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh, n\u00f3 \u1ee9c ch\u1ebf c\u00e2n b\u1eb1ng hai lo\u1ea1i topoisomerase lo\u1ea1i II kh\u00e1c nhau. S\u1ea3n ph\u1ea9m n\u00e0y c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i Neisseria gonorrhoeae v\u00e0 h\u1ea7u h\u1ebft c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u (nh\u01b0 Escherichia coli v\u00e0 Streptococcus pyogenes), bao g\u1ed3m c\u1ea3 c\u00e1c ch\u1ee7ng kh\u00e1ng thu\u1ed1c kh\u00e1ng sinh hi\u1ec7n nay. Do ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n c\u00e2n b\u1eb1ng t\u1ed1t c\u1ee7a Gepotidacin \u0111\u1ed1i v\u1edbi h\u1ea7u h\u1ebft c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh, c\u00e1c \u0111\u1ed9t bi\u1ebfn \u0111\u1eb7c hi\u1ec7u m\u1ee5c ti\u00eau \u0111\u01a1n l\u1ebb c\u00f3 th\u1ec3 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn ho\u1ea1t t\u00ednh c\u1ee7a n\u00f3.<\/p>\n\n\n\n
H\u01a1n n\u1eefa, ph\u1ed5 kh\u00e1ng khu\u1ea9n c\u1ee7a Gepotidacin ch\u1ee7 y\u1ebfu nh\u1eafm v\u00e0o c\u00e1c vi khu\u1ea9n gi\u1ed1ng Escherichia coli. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0, so v\u1edbi c\u00e1c lo\u1ea1i kh\u00e1ng sinh ph\u1ed5 r\u1ed9ng, kh\u1ea3 n\u0103ng g\u00e2y ra hi\u1ec7n t\u01b0\u1ee3ng kh\u00e1ng thu\u1ed1c \u1edf vi khu\u1ea9n c\u1ee7a n\u00f3 th\u1ea5p h\u01a1n. GSK d\u1ef1 \u0111o\u00e1n r\u1eb1ng Gepotidacin c\u00f3 th\u1ec3 \u0111\u1ea1t doanh thu h\u00e0ng n\u0103m cao nh\u1ea5t l\u00ean t\u1edbi 2 t\u1ef7 b\u1ea3ng Anh (kho\u1ea3ng 1.440 t\u1ef7 USD) trong t\u01b0\u01a1ng lai.<\/p>","protected":false},"excerpt":{"rendered":"
\u200cAccording to news reports from London, UK, pharmaceutical company GlaxoSmithKline (GSK) announced that the US Food and Drug Administration (FDA) has approved its supplemental new drug application for the novel oral antibiotic 750mg Gepotidacin tablets (brand name: “Blujepa”). This oral treatment is indicated for uncomplicated urethral and genital gonorrhea caused by susceptible Neisseria gonorrhoeae in […]<\/p>","protected":false},"author":2,"featured_media":973,"comment_status":"open","ping_status":"open","sticky":true,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,4],"tags":[],"class_list":["post-1033","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company-news","category-news"],"_links":{"self":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/1033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/comments?post=1033"}],"version-history":[{"count":1,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/1033\/revisions"}],"predecessor-version":[{"id":1034,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/posts\/1033\/revisions\/1034"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/media\/973"}],"wp:attachment":[{"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/media?parent=1033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/categories?post=1033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zenith-vn.com\/vi\/wp-json\/wp\/v2\/tags?post=1033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}